Duodenal Ulcers

How does BN help with Duodenal Ulcers?

Here is the answer from Dr. Masayuki Sano, MD — gastroenterologist, oncologist, and surgeon. He is a medical consultant for BN in Japan.

1) Causes of duodenal ulcers

The main causes of duodenal ulcers are:
1.H. pylori infection
2.NSAIDs (non-steroidal anti-inflammatory drugs)
3.Excess stomach acid
4.Reduced mucosal defense

2) Fundamental principle: The main treatment is “PPI” and “H. pylori eradication”For duodenal ulcers, the most important thing is to address the cause and control stomach acid:
Administer PPIs (proton pump inhibitors) to suppress acid secretion
Eradicate H. pylori if present
BN is not a replacement for these treatments. It is a supportive agent that helps create an
environment where the mucosa can recover more easily.

3) How BN supports treatment

◉ Antioxidant support (calming the inflammatory environment)
BN suppresses lipid peroxidation
→ Helps to gently regulate the inflammatory environment of the mucosa underlying the ulcer
◉ Digestive support (reducing gastrointestinal burden)
BN supports protein digestion
Promotes digestion
→ Reduces post-meal gastrointestinal stress, creating a gentler environment for the mucosa
◉ Gut environment support
As a fermented product, BN helps regulate the intestinal microbiome

4) Timing of use (safety-focused)
✅ Recommended timing
✔ Recovery phase when symptoms have settled
✔ Period of mucosal recovery (when PPIs have stabilized the stomach)

⚠ Acute phase (when there is pain, nausea, or suspected bleeding)
During the acute phase, priority should be given to:

• Medical intervention (PPIs, etc.)
• Excluding bleeding, perforation, or other complications

Even though BN is a food product, adding anything during the acute phase can sometimes trigger sensitive reactions.
→ It is safest to start BN after the acute phase has settled.

Ideally, it should be taken consistently for at least three months.
After that, it is recommended to continue with a maintenance dose.

5) 🍀 Summary
BN is best used as a supportive measure on top of standard treatment:

• Helps create an environment that does not interfere with mucosal recovery
• Supports a post-meal flow that does not overly burden the gastrointestinal tract

 

• The original source from Dr. Sano
• Translated document in English